Prolotherapy

Prolotherapy (also known as proliferative injection therapy) is an injection therapy whereby various solutions are injected into the tissues of a joint to stimulate a healing cascade.

There are various naming systems for types of prolotherapy.  One classification separates it into 3 types:  Inflammatory, Growth Factor stimulating, and Growth Factor injection, but this is not consistent throughout the literature at this time.  A good way to think of it, is that it “tricks” the body into thinking there has been a new injury so that it stimulates the body to heal itself.

While there are various studies arguing for and against the efficacy of prolotherapy, this, along with specific PT, gave me results.  There are also many support groups where patients attest that it significantly helped them, although this is anecdotal, as are all reports until someone does a controlled study.  Funding can be difficult for studies outside of the conventional medical system.

• Prolotherapy as an intervention for chronic, refractory musculoskeletal pain
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477775/
• Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders Injection Treatments
• https://www.caringmedical.com/prolotherapy-news/prolotherapy-ehlers-danlos-syndrome/